I mean, that was literally the elevator pitch for the show - Sherlock Holmes as an American doctor. They even made a point in casting of not wanting a British actor which makes it even funnier that Hugh Laurie got the part.
Holmes = House
Watson = Wilson
7% solution of cocaine = Vicodin
The biggest difference is that he’s essentially his own Moriarty, and his Reichenbach Falls involved a burning house, heroin and hallucinations of dead former team members.
I mean, that was literally the elevator pitch for the show - Sherlock Holmes as an American doctor. They even made a point in casting of not wanting a British actor which makes it even funnier that Hugh Laurie got the part.
Holmes = House Watson = Wilson 7% solution of cocaine = Vicodin
The biggest difference is that he’s essentially his own Moriarty, and his Reichenbach Falls involved a burning house, heroin and hallucinations of dead former team members.