20Mtf 🏳️‍⚧️
Playing life on New Girl+ 💄
Prog addict and needle enthusiast 💊💉
Chronic hornyposter and oversharer 🩷
Proudly European 🇨🇿

HRT since 12.2.2026
Taken 31.3.2024

  • 71 Posts
  • 469 Comments
Joined 16 days ago
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Cake day: September 25th, 2026

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  • Okay, let me explain…
    inhales

    Valerate is an estradiol ester, estradiol valerate. All esters are injectable and they’re called prodrugs. It means what you’re injecting isn’t actually the drug itself (estradiol, in this case), but an ester of that drug. And that ester is then slowly converted to the target drug in your body.
    How quickly or slowly it converts depends on the ester. They’re all estrogen, but they have different half lives and different curves (E2 levels in blood at certain times). If you really wanna get into that, here’s a simulator where you can play around with all major estradiol esters.
    I use valerate and I joke that I hate my thighs. It’s because valerate lasts the shortest amount of time (it’s said 7 days) and I personally have to do intramuscular injections every 3 days with a big ass needle. Valerate is the most commonly prescribed ester, probably the one you’ll get if you’re going official.
    DIY is usually enanthate, which actually lasts a whole week and has more stable levels (less ups and downs, less mood swings). I’m official so I just rawdog valerate, lol.

    CPA (cyproterone acetate) on the other hand is an anti-androgen (AA for short), a T-blocker. It blocks testosterone, duh. This AA is…special. It has side effects, but it’s also an extremely strong blocker, it nukes testosterone. The side effects are…something. For one, long-term it can cause meningiomas and prolactinomas (both types of benign brain tumors). It’s also bad for your liver.
    In addition to that, it raises a hormone called prolactin, a lot. Prolactin does a whole bunch, but it’s best known for inducing lactation. High prolactin is NOT good, so if you ever start lactating for no reason, go see a freaking doctor, but that’s what I was joking about, lactation.

    Whew. This is my hyperfixation tbh. I…may be slightly autistic 😆
    Probably not tho