• outbound@lemmy.ca
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    1 year ago

    As a Type II diabetic:

    fuck

    As a punk:

    All I wanted was a Pepsi
    Just one Pepsi

    *Diet Pepsi contains sucralose, not aspertame, so I guess I’m good (for now)

  • null_@lemmy.world
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    1 year ago

    There is a lot of public misunderstanding of the rodent studies that linked aspartame to cancer, which are very flawed and essentially come from a single Italian research group.

    There is still no definitive link to cancer risk in humans so I would continue to be skeptical. The maximum recommended safe exposure for aspartame is the equivalent of 12 cans of coke, and the strong effects from the rodent study were using exposure amounts equivalent to 5 times that amount, or 60 cans daily, every day of their life after day 12 of fetal life (i.e. before birth).

    Almost anything can cause long-term health risks and toxicity at such massive exposure levels.

    https://www.cancer.org/cancer/risk-prevention/chemicals/aspartame.html

    Link to the free Pubmed link to one of the original source studies from 2008 so you can see their methodology and the absurdly massive exposure amounts needed to ovserve these effects:

    https://pubmed.ncbi.nlm.nih.gov/17805418/

    • Burstar@lemmy.dbzer0.com
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      1 year ago

      I disagree with the ‘massive’ exposure ‘needed’ to observe these effects exaggeration. First, the point of the study was to show it can be carcinogenic, not to parse at exactly what level in humans. Second, effects are seen at the 400ppm level which equates to 20mg/kg. This is 1600mg/day or 8 cans of Diet Coke (@200mg/can) for an 80kg male. That is NOT an impossible level of daily consumption for many.

      I suspect further research was done to confirm your linked studies and refine exactly at what minimum levels of daily consumption elicit carcinogenic effects. That will likely be in the full report once released. Until then, you sound like you don’t want it to be true, rather than an impartial evaluator of the research.

    • P03 Locke@lemmy.dbzer0.com
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      1 year ago

      the strong effects from the rodent study were using exposure amounts equivalent to 5 times that amount, or 60 cans daily, every day of their life after day 12 of fetal life (i.e. before birth).

      This is why I hate rodent studies. They always up the exposure to whatever they are testing to hyper-extreme limits. Then point their flawed results to the world and declare “See! X causes Y!”

      There are even similar rat studies for marijuana that try to link it to cancer as well, despite the fact that zero people have actually died from weed. It’s all overblown bullshit.

      • ██████████@lemmy.world
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        1 year ago

        Dude have you seen how many diet Cokes people drink? Liters and liters daily. Not excessive at all honestly considering LifeTime total exposure

        Im a chemist by trade. This is actually chemically very simple. I only looked deeply into Sucralose Splenda. So I’ll discuss that

        These have Chlorine molecules. A very electrophilic element even in a chemical bond. Meaning it can cause reactions in other molecules very easily. Sucralose has Three Chlorines. If it touches DNA it’s bad business man.

        I love diet Coke btw lol I could drink 5 gallons right now idk I smoke cigs. But don’t sugar coat it